Medically reviewed by Dr. Reina Punj, MBBS, PG Diploma in Endocrinology (University of South Wales), Lead Physician, Excelgenics Clinical Panel.
Tired, Wired and Running on Empty
Modern working life rewards long hours and constant availability. The result, for many, is a persistent sense of being simultaneously exhausted and unable to switch off.
Nutrition is only one part of that picture, but magnesium contributes to normal psychological function, normal nervous system function and the reduction of tiredness and fatigue, and diets low in whole grains, pulses, nuts, seeds and leafy greens can fall short of recommended intakes. For more on forms, dosage and safety, see our Magnesium Supplements Guide.
How Magnesium Supports the Nervous System

Magnesium contributes to normal nervous system function. Researchers have also studied its relationship with the hypothalamic-pituitary-adrenal (HPA) axis, the system involved in the body's stress response.
The pathways researchers have examined include:
- Modulation of NMDA receptors, which are involved in nerve-cell excitability
- Interaction with GABA receptors, part of the brain's calming system
- Possible links with cortisol, the main stress hormone
- Involvement in serotonin signalling
This is an active research area; these mechanisms do not show that a supplement will change how stressed you feel.
Low dietary magnesium intake has been associated with:
- Feeling tense or on edge
- Difficulty settling in the evening
- Muscle tension and cramps
- Tiredness and difficulty concentrating
- Low resilience to everyday pressure
These are non-specific. If they persist, speak to a qualified healthcare professional rather than assuming a nutritional cause.
Why Some Magnesium Supplements Fall Short
Inexpensive magnesium salts such as oxide are poorly absorbed and are more likely to upset the digestive tract, which is unhelpful for anyone already feeling run down.
Magneva uses magnesium bisglycinate, a chelated form chosen for absorption and tolerability:
- Chelated to glycine, an amino acid
- Better absorbed than magnesium oxide, as organic and chelated forms generally are
- Generally well tolerated for daily use, although loose stools, nausea or stomach cramps can occur
Each tablet provides:
- 350 mg elemental magnesium (from 1,590 mg magnesium bisglycinate)
- 1.9 mg vitamin B6, which contributes to normal psychological function and the reduction of tiredness and fatigue
- A vegan tablet, taken once a day
- Made under an FSSAI licence
Who Might Consider Magneva

- Professionals managing high cognitive loads
- Women balancing work, caregiving and changing routines
- Students under academic pressure
- Active individuals focused on recovery
- Anyone whose diet is low in magnesium-rich foods
What to Expect
Individual responses vary and there is no fixed timeline. Magnesium is a nutrient, not a quick fix: think in weeks of consistent use alongside sleep, movement and a balanced diet.
How to Take It
- 1 tablet daily, preferably 30–60 minutes before bedtime, with water or a light meal
- Do not exceed the recommended daily dose. The NIH upper limit for magnesium from supplements is 350 mg a day for adults, and one tablet provides 350 mg, so do not take other magnesium supplements alongside it
- Possible side effects include loose stools, nausea and stomach cramps
- If you have kidney disease, use magnesium only on medical advice
- Leave a gap between magnesium and some antibiotics or bisphosphonates
The Nutritional Foundation of Calm
Meditation, journalling and better boundaries all help. But if magnesium intake is low, the nutritional foundation those habits rest on is incomplete.
Magneva is not a stimulant and not a sedative. It is a well-tolerated form of an essential mineral that contributes to normal nervous system and psychological function. If you are experiencing persistent anxiety, low mood or exhaustion, please speak to a qualified healthcare professional.
This article is for general education and is not medical advice. Food supplements are not intended to diagnose, treat, cure or prevent any disease. Consult a qualified healthcare professional before starting any supplement, particularly if you are pregnant, breastfeeding, have a medical condition or take medication.






